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Biomedical engineering

In vitro amniogenesis

Using a biomimetic culture platform to replicate the early biophysical environment of a developing embryo, human pluripotent stem cells can be directed towards amnion formation in vitro.

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Figure 1: Development of the amnion.
Figure 2: Development of squamous cysts from human pluripotent stem cells on a synthetic, soft artificial matrix.


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Correspondence to Martin Pera.

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Pera, M. In vitro amniogenesis. Nature Mater 16, 394–395 (2017).

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