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Tissue engineering

Signals from within

A regenerative cardiac patch with integrated freestanding electrodes allows the electrical stimulation and recording of cardiomyocyte growth and activity, with on-demand drug delivery.

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Figure 1: An illustration of patch fabrication.
Figure 2: Patch morphology and application.

References

  1. Bergmann, O. et al. Science 324, 98–102 (2009).

    Article  CAS  Google Scholar 

  2. Nunes, S. S. et al. Nature Methods 10, 781–787 (2013).

    Article  CAS  Google Scholar 

  3. Radisic, M. et al. Proc. Natl Acad. Sci. USA 101, 18129–18134 (2004).

    Article  CAS  Google Scholar 

  4. Hirt, M. N. et al. J. Mol. Cell. Cardiol. 74, 151–161 (2014).

    Article  CAS  Google Scholar 

  5. Bursac, N. et al. Am. J. Physiol. 277, 433–444 (1999).

    Google Scholar 

  6. Feiner, R. et al. Nature Mater. 15, 679–685 (2016).

    Article  CAS  Google Scholar 

  7. Chong, J. J. et al. Nature 510, 273–277 (2014).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Milica Radisic.

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Radisic, M. Signals from within. Nature Mater 15, 596–597 (2016). https://doi.org/10.1038/nmat4648

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