Whether two species will co-crystallize depends on the chemical, physical and structural complementarity of the interacting components. Here, by using DNA as a surface ligand, we selectively co-crystallize mixtures of two different anisotropic nanoparticles and systematically investigate the effects of nanoparticle size and shape complementarity on the resultant crystal symmetry, microstrain, and effective ‘DNA bond’ length and strength. We then use these results to understand a more complicated system where both size and shape complementarity change, and where one nanoparticle can participate in multiple types of directional interactions. Our findings offer improved control of non-spherical nanoparticles as building blocks for the assembly of sophisticated macroscopic materials, and provide a framework to understand complementarity and directional interactions in DNA-mediated nanoparticle crystallization.
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C.A.M. acknowledges support from the following awards: the Air Force Office of Scientific Research (AFOSR) Multidisciplinary University Research Initiative (MURI) FA9550-11-1-0275, the Department of Defense National Security Science and Engineering Faculty Fellowship (NSSEFF) award N00014-15-1-0043, the National Science Foundation (NSF) Materials Research Science and Engineering Center program DMR-1121262 at the Materials Research Center of Northwestern University, and the Non-equilibrium Energy Research Center (NERC)—an Energy Frontier Research Center funded by the Department of Energy (DoE), Office of Science, and Office of Basic Energy Sciences under Award DE-SC0000989. M.N.O. and M.R.J. are grateful to the NSF for Graduate Research Fellowships. SAXS experiments were carried out at the Dupont–Northwestern–Dow Collaborative Access Team beamline at the Advanced Photon Source (APS) at Argonne National Laboratory, and use of the APS was supported by the DoE (DE-AC02-06CH11357). This work made use of the EPIC facility (NUANCE Center-Northwestern University), which has received support from the MRSEC programme (NSF DMR-1121262) at the Materials Research Center, and the Nanoscale Science and Engineering Center (EEC-0118025/003), both programmes of the National Science Foundation, the State of Illinois and Northwestern University. We thank K. A. Brown and A. J. Senesi for helpful discussions.
The authors declare no competing financial interests.
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O’Brien, M., Jones, M., Lee, B. et al. Anisotropic nanoparticle complementarity in DNA-mediated co-crystallization. Nature Mater 14, 833–839 (2015). https://doi.org/10.1038/nmat4293
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