Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Bioactive hydrogels

Lighting the way

Nature Materials volume 12, pages 950–952 (2013)Cite this article

Subjects

Advances in photochemistry have profoundly impacted the way in which biology is studied. Now, a photoactivated enzymatic patterning method that offers spatiotemporal control over the presentation of bioactive proteins to direct cells in three-dimensional culture significantly expands the available chemical toolbox.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Light-activated enzymatic protein patterning in hydrogels offers control of directed cell migration1.

References

  1. Mosiewicz, K. A. et al. Nature Mater. 12, 1072–1078 (2013).

    Article  CAS  Google Scholar 

  2. Tsien, R. Y. Angew. Chem. Int. Ed. 48, 5612–5626 (2009).

    Article  CAS  Google Scholar 

  3. Losonczy, A. & Magee, J. C. Neuron 50, 291–307 (2006).

    CAS  Google Scholar 

  4. Lee, S.-H., Moon, J. J. & West, J. L. Biomaterials 29, 2962–2968 (2008).

    Article  CAS  Google Scholar 

  5. DeForest, C. A., Polizzotti, B. D. & Anseth, K. S. Nature Mater. 8, 659–664 (2009).

    Article  CAS  Google Scholar 

  6. Alge, D. L., Azagarsamy, M. A., Donohue, D. F. & Anseth, K. S. Biomacromolecules 14, 949–953 (2013).

    Article  CAS  Google Scholar 

  7. Culver, J. C. et al. Adv. Mater. 24, 2344–2348 (2012).

    Article  CAS  Google Scholar 

  8. Kloxin, A. M., Kasko, A. M., Salinas, C. N. & Anseth, K. S. Science 324, 59–63 (2009).

    Article  CAS  Google Scholar 

  9. Wirkner, M. et al. Adv. Mater. 23, 3907–3910 (2011).

    Article  CAS  Google Scholar 

  10. Griffin, D. R. et al. Biomacromolecules 14, 1199–1207 (2013).

    Article  CAS  Google Scholar 

  11. DeForest, C. A. & Anseth, K. S. Angew. Chem. Int. Ed. 51, 1816–1819 (2012).

    Article  CAS  Google Scholar 

  12. Guvendiren, M. & Burdick, J. A. Nature Commun. 3, 792 (2012).

    Article  Google Scholar 

  13. Luo, Y. & Shoichet, M. S. Nature Mater. 3, 249–253 (2004).

    Article  CAS  Google Scholar 

  14. Wylie, R. G. et al. Nature Mater. 10, 799–806 (2011).

    Article  CAS  Google Scholar 

  15. Zisch, A. H., Schenk, U., Schense, J. C., Sakiyama-Elbert, S. E. & Hubbell, J. A. J. Control. Release 72, 101–113 (2001).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Daniel L. Alge and Kristi S. Anseth are at the Department of Chemical and Biological Engineering, the BioFrontiers Institute, and the Howard Hughes Medical Institute, University of Colorado at Boulder, Boulder, Colorado 80303, USA,

    Daniel L. Alge & Kristi S. Anseth

Authors
  1. Daniel L. Alge
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kristi S. Anseth
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kristi S. Anseth.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Alge, D., Anseth, K. Lighting the way. Nature Mater 12, 950–952 (2013). https://doi.org/10.1038/nmat3794

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmat3794

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing