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Cell migration

Towards the void

Nature Materials volume 12, pages 783–784 (2013)Cite this article

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Cells at the edges of migrating epithelial sheets pull themselves towards unfilled space regardless of their direction of motion.

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Figure 1: Colour maps of traction forces exerted on an underlying elastic substrate by a migrating cell sheet approaching and surrounding a non-adhesive island (values are averages of six identical cell sheets)3.
Figure 2: Heterogeneity in cell shape within a migrating cell sheet downstream of a non-adhesive island3.

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Authors and Affiliations

  1. Eric R. Dufresne is at the Departments of Mechanical Engineering and Materials Science, Chemical and Environmental Engineering, Applied Physics, Physics, and Cell Biology, Yale University, 9 Hillhouse Avenue, New Haven, Connecticut 06511, USA,

    Eric R. Dufresne

  2. Departments of Internal Medicine and Cell Biology, Martin A. Schwartz is at the Yale Cardiovascular Research Center, Yale School of Medicine, 300 George Street, New Haven, Connecticut 06511, USA,

    Martin A. Schwartz

Authors
  1. Eric R. Dufresne
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  2. Martin A. Schwartz
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Correspondence to Eric R. Dufresne or Martin A. Schwartz.

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Dufresne, E., Schwartz, M. Towards the void. Nature Mater 12, 783–784 (2013). https://doi.org/10.1038/nmat3743

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