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Nanoparticle self-assembly

Bonding them all

A general approach for decorating nanoparticles with a highly dense shell of DNA linkers expands the range of building blocks that can be used for DNA-mediated nanoparticle self-assembly.

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Figure 1: Synthesis of nanoparticle-based PAEs.
Figure 2: Binary superlattices from arbitrary combinations of QD (blue), Fe3O4 (red) and Au (yellow) PAEs.


  1. Schmid, G. (ed.) Nanoparticles – From Theory to Application 2nd edn (Wiley, 2010).

    Book  Google Scholar 

  2. Talapin, D. V., Lee, J.-S., Kovalenko, M. V. & Shevchenko, E. V. Chem. Rev. 110, 389–458 (2010).

    Article  CAS  Google Scholar 

  3. Zhang, C. et al. Nature Mater. 12, 741–746 (2013).

    Article  CAS  Google Scholar 

  4. Mirkin, C. A., Letsinger, R. L., Mucic, R. C. & Storhoff, J. J. Nature 382, 607–609 (1996).

    Article  CAS  Google Scholar 

  5. Alivisatos, A. P. et al. Nature 382, 609–611 (1996).

    Article  CAS  Google Scholar 

  6. Park, S. et al. Nature 451, 553–556 (2008).

    Article  CAS  Google Scholar 

  7. Nykypanchuk, D., Maye, M. M., van der Lelie, D. & Gang, O. Nature 451, 549–552 (2008).

    Article  CAS  Google Scholar 

  8. Agard, N. J., Prescher, J. A. & Bertozzi, C. R. J. Am. Chem. Soc. 126, 15046–15047 (2004).

    Article  CAS  Google Scholar 

  9. Pauling, L. The Nature of the Chemical Bond 3rd edn (Cornell Univ. Press, 1960).

    Google Scholar 

  10. Macfarlane, R. J. et al. Science 334, 204–208 (2011).

    Article  CAS  Google Scholar 

  11. Cutler, J. I., Auyeung, E. & Mirkin, C. A. J. Am. Chem. Soc. 134, 1376–1391 (2012).

    Article  CAS  Google Scholar 

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Correspondence to Ulrich Simon.

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Simon, U. Bonding them all. Nature Mater 12, 694–696 (2013).

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