Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cancer therapy

Death by magnetism

A magnetic on/off switch for cell-death signalling in cancer cells is developed using antibodies conjugated to magnetic nanoparticles. The control of cell death in in vivo systems is demonstrated by a tell-tale morphological change within the zebrafish.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: A schematic showing the magnetic influences on receptor-bound magnetic nanoparticles depending on the nature of the magnetic field applied.

References

  1. Cho, M. H. et al. Nature Mater. 11, 1038–1043 (2012).

    Article  CAS  Google Scholar 

  2. Pankhurst, Q. A., Thanh, N. K. T., Jones, S. & Dobson, J. J. Phys D 42, 224001 (2009).

    Article  Google Scholar 

  3. Brazel, C. S. Pharma. Res. 26, 644–656 (2009).

    Article  CAS  Google Scholar 

  4. Kim, D-H. et al. Nature Mater. 9, 165–171 (2010).

    Article  CAS  Google Scholar 

  5. Dobson, J. Nature Nanotech. 3, 139–143 (2008).

    Article  CAS  Google Scholar 

  6. Dobson, J., Cartmell, S. H., Keramane, A. & El Haj, A. J. IEEE Trans. NanoBioSci. 5, 173–177 (2006).

    Article  Google Scholar 

  7. Kanczler, J. M. et al. Tissue Eng. 16, 3241–3250 (2010).

    Article  CAS  Google Scholar 

  8. Mannix, R. J. et al. Nature Nanotech. 3, 36–40 (2008).

    Article  CAS  Google Scholar 

  9. Creixelle, M., Bohorquez, A. C., Torres-Lugo, M. & Rinaldi, C. ACS Nano 5, 7124–7129 (2011).

    Article  Google Scholar 

  10. Huang, H. et al. Nature Nanotech. 5, 602–606 (2010).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jon Dobson.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dobson, J. Death by magnetism. Nature Mater 11, 1006–1008 (2012). https://doi.org/10.1038/nmat3501

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmat3501

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing