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Are thalamocortical rhythms the rosetta stone of a subset of neurological disorders?

Abstract

Recent evidence indicates that "dysrhythmias" cause alterations in the normal function of the thalamocortical loop and lead to various types of neurological disorders. Will decoding this rhythm help us to understand the basis for movement disorders, chronic pain, and even neuropsychological dysfunction?

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Figure 1: Properties of activity in the thalamocortical circuit.

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McCormick, D. Are thalamocortical rhythms the rosetta stone of a subset of neurological disorders?. Nat Med 5, 1349–1351 (1999). https://doi.org/10.1038/70911

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