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SOD1 aggregates in ALS: Cause, correlate or consequence?

Abstract

Increased expression of wild-type SOD1 in mice with ALS does not slow disease progression or diminish the pathological changes in motor neurons.

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Brown, R. SOD1 aggregates in ALS: Cause, correlate or consequence?. Nat Med 4, 1362–1364 (1998). https://doi.org/10.1038/3945

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