Autoantigen administration in an animal model of diabetes prevents development of the disease even after insulitis is established (pages 1348–1353).
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Solimena, M., Camilli, P. From Th1 to Th2: Diabetes immunotherapy shifts gears. Nat Med 2, 1311–1312 (1996). https://doi.org/10.1038/nm1296-1311
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DOI: https://doi.org/10.1038/nm1296-1311