Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Patent-sharing scheme for neglected diseases may have catch

Diseases that disproportionally afflict the world's poor provide few incentives for profit-seeking drug companies. In the past couple of years, collaborative patent-sharing schemes have popped up to remedy this by helping drugmakers develop low-cost medicines for less developed nations. Last year, for example, UNITAID launched the Medicines Patent Pool (MPP), which focuses on HIV drugs. Now, the World Intellectual Property Organization (WIPO), a Geneva-based arm of the UN, is getting into the game with a new open-access resource aimed at tackling malaria, tuberculosis and neglected tropical diseases.

The database, called WIPO Re:Search, was launched in late October in partnership with the Washington, DC–based nonprofit BIO Ventures for Global Health (BVGH). Since January of last year, BVGH has also administered the Pool for Open Innovation against Neglected Tropical Diseases (POINT), initially formed by the British drug giant GlaxoSmithKline. But that database has failed to attract many other major industrial partners, and organizers hope that WIPO Re:Search will grow to ultimately supplant it.

Like the POINT project, WIPO's resource compiles intellectual property beyond patents, including assets related to many steps in the drug development process, such as research tools, manufacturing technology and both experimental and marketed compounds. However, it is far more extensive, with contributions from eight major pharmaceutical companies and a dozen nonprofit research organizations from around the world. The database is available to all scientists and drugmakers free of charge as long as they agree that any therapies stemming from the information are sold at cost of production to the UN's list of the 48 least developed countries in the world.

Stephen Maurer, who studies innovation and science policy at the University of California–Berkeley School of Law, thinks that sharing nonpatented proprietary information, previously held hostage by institutions, is the database's major contribution. “This is a good first step in terms of getting out of this problem that intellectual property does nothing for the developing world,” he says.

However, Michelle Childs, director of policy and advocacy at the Médecins Sans Frontières Campaign for Access to Essential Medicines in Geneva, worries that by only making drugs available to the most impoverished nations, WIPO Re:Search—like other patent pools before it—could leave out people in middle-income countries who can't afford full-price medicines (see Nat. Med. 17, 1023–1023, 2011). “Restricting access to the least developed countries is just ignoring where people with neglected tropical diseases live,” Childs says. “By agreeing to licensing terms that have such an unacceptably limited geographical scope, the UN—a norm-setting agency—is setting a bad precedent for future licensing arrangements.”

And, without concrete targets, some experts worry whether the initiative will actually deliver on its stated goal of promoting the development of new drugs, vaccines and diagnostics. “Statements of goodwill made in good faith are not good enough,” says MPP head Ellen 't Hoen. “Actual action needs to be put behind it.”

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Waters, H. Patent-sharing scheme for neglected diseases may have catch. Nat Med 17, 1529 (2011). https://doi.org/10.1038/nm1211-1529a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm1211-1529a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing