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Cracking the moody brain: Lifting the mood with ketamine

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Figure 1: The rapid-acting antidepressant effects of ketamine and the potential role of synaptogenic and neurotrophic mechanisms in depression.


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Correspondence to James W Murrough.

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Competing interests

D.S.C. and Mount Sinai School of Medicine have been named on a use patent of ketamine for the treatment of depression. If ketamine were shown to be effective in the treatment of depression and approved by the US Food and Drug Administration for this indication, D.S.C. and Mount Sinai School of Medicine could benefit financially.

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Murrough, J., Charney, D. Cracking the moody brain: Lifting the mood with ketamine. Nat Med 16, 1384–1385 (2010).

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