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Saving the skin from drug-induced detachment

Nature Medicine volume 14, pages 13111313 (2008) | Download Citation

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Granulysin, a powerful cytolytic protein secreted from immune cells, underlies an extreme and deadly response to common medications, in which the skin blisters and sloughs off. The findings may also have implications for bone marrow transplant recipients suffering from graft-versus-host disease (pages 1343–1350).

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Affiliations

  1. Brian J. Nickoloff is at the Loyola University of Chicago Medical Center, Building 112, Room 301, 2160 South First Avenue, Maywood, Illinois 60153-5385, USA.  bnickol@lumc.edu

    • Brian J Nickoloff

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DOI

https://doi.org/10.1038/nm1208-1311

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