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Putting the heat on cancer

Two studies highlight the role of the heat shock response in initiating and maintaining cancer.

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Figure 1: HSP90 and HSF1 regulate tumor cell survival.

Kim Caesar

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Competing interests

P.W. has developed HSP90 inhibitors that are licensed to Vernalis and Novartis. He has received research funding from Vernalis and is a consultant to Novartis.

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Workman, P., de Billy, E. Putting the heat on cancer. Nat Med 13, 1415–1417 (2007). https://doi.org/10.1038/nm1207-1415

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