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Aneurysm treatments expand

Abdominal aortic aneurysms arise from chronic, irreversible destruction of connective tissue. A promising pharmacologic approach not only suppresses development of aneurysms, but also induces regression (pages 1330–1338).

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Figure 1: Aneurysms regress after inhibition of JNK activation.

Katie Ris


  1. Thompson, R.W., Geraghty, P.J. & Lee, J.K. Curr. Prob. Surg. 39, 93–232 (2002).

    Article  Google Scholar 

  2. Yoshimura, K. et al. Nat. Med. 11, 1330–1338 (2005).

    Article  CAS  Google Scholar 

  3. The UK Small Aneurysm Trial Participants. Lancet 352, 1649–1655 (1998).

  4. Lederle, F.A. et al. N. Engl. J. Med. 346, 1437–1444 (2002).

    Article  Google Scholar 

  5. Wassef, M. et al. J. Vasc. Surg. 34, 730–738 (2001).

    Article  CAS  Google Scholar 

  6. Pyo, R. et al. J. Clin. Invest. 105, 1641–1649 (2000).

    Article  CAS  Google Scholar 

  7. Longo, G.M. et al. J. Clin. Invest. 110, 625–632 (2002).

    Article  CAS  Google Scholar 

  8. Manning, M.W., Cassis, L.A. & Daugherty, A. Arterioscler. Thromb. Vasc. Biol. 23, 483–488 (2003).

    Article  CAS  Google Scholar 

  9. Mosorin, M. et al. J. Vasc. Surg. 34, 606–610 (2001).

    Article  CAS  Google Scholar 

  10. Baxter, B.T. et al. J. Vasc. Surg. 36, 1–12 (2002).

    Article  Google Scholar 

  11. Han, Z. et al. J. Clin. Invest. 108, 73–81 (2001).

    Article  CAS  Google Scholar 

  12. Matsumura, J.S., Pearce, W.H., McCarthy, W.J. & Yao, J.S. J. Vasc. Surg. 25, 113–123 (1997).

    Article  CAS  Google Scholar 

  13. Allaire, E. et al. Ann. Surg. 239, 417–427 (2004).

    Article  Google Scholar 

  14. Zarins, C.K. et al. Eur. J. Vasc. Endovasc. Surg. 29, 496–503 (2005).

    Article  CAS  Google Scholar 

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Thompson, R. Aneurysm treatments expand. Nat Med 11, 1279–1281 (2005).

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