Gallstones develop in response to an imbalance of lipids in bile, the digestive fluid produced in the liver. A compound that restores the balance prevents gallstone formation in mouse models (pages 1352–1358).
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Goralski, K., Sinal, C. Chipping away at gallstones. Nat Med 10, 1301–1302 (2004). https://doi.org/10.1038/nm1204-1301
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DOI: https://doi.org/10.1038/nm1204-1301