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West Nile virus: crossing the blood-brain barrier

A study in mice traces the path of West Nile virus into the brain. Viral replication in peripheral tissues triggers a Toll-like receptor inflammatory response that alters the blood-brain barrier (pages 1366–1373).

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Figure 1: West Nile crossing.

Deborah Maizels


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Diamond, M., Klein, R. West Nile virus: crossing the blood-brain barrier. Nat Med 10, 1294–1295 (2004).

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