The most common form of inherited peripheral neuropathy results from overexpression of a single gene. Simple application of an antiprogesterone drug can reduce gene expression and alleviate symptoms in a rat model (pages 1533–1537).
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De Jonghe, P., Timmerman, V. Anti-steroid takes aim at neuropathy. Nat Med 9, 1457–1458 (2003). https://doi.org/10.1038/nm1203-1457
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DOI: https://doi.org/10.1038/nm1203-1457