Abstract
The lymphoid system is known to be involved in the propagation and spread of scrapie. However, the identity of the cell type responsible for scrapie replication remains controversial. A new study provides evidence that the follicular dendritic cells in the spleen are the targets of this infectious form of prion (pages 1308–1312).
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Sy, MS., Gambetti, P. Prion replication—once again blaming the dendritic cell. Nat Med 5, 1235–1237 (1999). https://doi.org/10.1038/15186
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DOI: https://doi.org/10.1038/15186
