Internalization of targeted therapeutics is often needed for efficacy, but also alters drug penetration of a tissue. A new model explores the trade-offs of intracellular drug trafficking.
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Stokes, C. The pros and cons of drug ‘trafficking’. Nat Med 1, 1135–1136 (1995). https://doi.org/10.1038/nm1195-1135
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DOI: https://doi.org/10.1038/nm1195-1135