Stem cells: the good, bad and barely in control

The goal of replacing dying cells in Parkinson disease with stem cells is now brought a step closer to the clinic. A new protocol eases symptoms in a rat model of the disease, but also raises the concern that poorly differentiated cells have the potential to become tumorigenic (pages 1259–1268).

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Figure 1: Imperfect transplant.

Jamie Simon

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Carson, C., Aigner, S. & Gage, F. Stem cells: the good, bad and barely in control. Nat Med 12, 1237–1238 (2006). https://doi.org/10.1038/nm1106-1237

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