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TLRs play good cop, bad cop in the lung

Nature Medicine volume 11, pages 1161–1162 (2005)Cite this article

Toll-like receptors act as mediators of injury or repair in the inflamed lung, and the balance depends on the integrity of a component of the extracellular matrix (pages 1173–1179).

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Figure 1: Jiang et al. found that TLR2 and TLR4 act as key sensors of the extracellular matrix component hyaluronan in the lung.

Katie Ris

References

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  1. School of Biochemistry and Immunology, Trinity College, Dublin, 2, Ireland

    Luke A J O'Neill

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  1. Luke A J O'Neill
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O'Neill, L. TLRs play good cop, bad cop in the lung. Nat Med 11, 1161–1162 (2005). https://doi.org/10.1038/nm1105-1161

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