Male fertility is dependent on dipeptidase activity of testis ACE

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Figure 1: Creation and analysis of mutant mice.

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Acknowledgements

This work was supported by US National Institutes of Health (NIH) grants DK39777, DK51445 and DK55503 (to K.B.), HD23479 (to B.D.S.), F32 DK065410 (to K.F.) and T32 GM08367 (to R.L.), the National Kidney Foundation (to S.F.) and a Scientist Development Grant from the American Heart Association (to H.D.X.). SPAM1-specific antibody was a gift from P. Martin-De Leon (University of Delaware). The authors also thank P. Selvaraj for constructive discussions.

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Fuchs, S., Frenzel, K., Hubert, C. et al. Male fertility is dependent on dipeptidase activity of testis ACE. Nat Med 11, 1140–1142 (2005) doi:10.1038/nm1105-1140

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