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Getting the T-box dose right

Nature Medicine volume 7, pages 1185–1186 (2001)Cite this article

Holt–Oram syndrome has been associated with mutations in the T-box transcription factor TBX5, but little is known about the function of this protein or how mutations in it cause disease. A new mouse model of this syndrome will help to answer some of these questions.

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Authors and Affiliations

  1. Cardiology Division Department of Medicine and Department of Cell Biology Weill Medical College of Cornell University, Molecular Cardiology Laboratory, New York, New York, USA

    Cathy J. Hatcher & Craig T. Basson

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  1. Cathy J. Hatcher
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  2. Craig T. Basson
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Hatcher, C., Basson, C. Getting the T-box dose right. Nat Med 7, 1185–1186 (2001). https://doi.org/10.1038/nm1101-1185

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