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A sweet path toward tolerance in the gut

Nature Medicine volume 16, pages 10761077 (2010) | Download Citation

Uncovering how the immune system of the mucosa surmounts allergic reactions may open new avenues to treat inflammatory conditions in the gut. New findings in mice now show that a C-type lectin receptor in dendritic cells (DCs) protects against food antigens that cause systemic anaphylaxis—promoting oral tolerance (pages 1128–1133).

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Author information

Affiliations

  1. Gabriel A. Rabinovich is at the Laboratorio de Inmunopatología, Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina and the Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.

    • Gabriel A Rabinovich

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Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to Gabriel A Rabinovich.

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DOI

https://doi.org/10.1038/nm1010-1076

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