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Stem cells on the move

Nature Medicine volume 16, pages 1073–1074 (2010)Cite this article

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Mobilization of hematopoietic stem cells (HSCs) from the bone marrow is the standard method to collect grafts for stem cell transplants, but sometimes insufficient HSCs are mobilized. A new study suggests that epidermal growth factor receptor (EGFR) inhibition can augment mobilization, bringing us one step closer to an universal method to obtain HSCs for transplantation (pages 1141–1146).

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Figure 1: EGFR signaling inhibits HSPC mobilization from the bone marrow.

Marina Corral

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  1. Daniel Link is Alan and Edith Wolff Professor of Medicine and Pathology & Immunology at Washington University School of Medicine, St. Louis, Missouri, USA.,

    Daniel Link

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Correspondence to Daniel Link.

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Link, D. Stem cells on the move. Nat Med 16, 1073–1074 (2010). https://doi.org/10.1038/nm1010-1073

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