Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Autoantibodies vex the vasculature

Infections with fimbriated bacteria may trigger autoimmunity and cause a form of severe vasculitis that affects capillaries in the kidney and that can destroy the organ (pages 1088–1096).

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Human LAMP-2 induces glomerular endothelial injury.

Kim Caesar

References

  1. Jennette, J.C. et al. Arthritis Rheum. 37, 187–192 (1994).

    Article  CAS  PubMed  Google Scholar 

  2. Kain, R. et al. Nat. Med. 14, 1088–1096 (2008)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Jennette, J.C. & Falk, R.J. N. Engl. J. Med. 337, 1512–1523 (1997).

    Article  CAS  PubMed  Google Scholar 

  4. Kallenberg, C.G.M., Heeringa, P. & Stegeman, C.A. Nat. Clin. Pract. Rheumatol. 2, 661–670 (2006).

    Article  CAS  PubMed  Google Scholar 

  5. Boomsma, M.M. et al. Arthritis Rheum. 43, 2025–2033 (2000).

    Article  CAS  PubMed  Google Scholar 

  6. Xiao, H. et al. J. Clin. Invest. 110, 955–963 (2002).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Pfister, H. et al. Blood 104, 1411–1418 (2004).

    Article  CAS  PubMed  Google Scholar 

  8. van der Geld, Y.M., et al. Ann. Rheum. Dis. 66, 1679–1682 (2007).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Kain, R. et al. J. Exp. Med. 181, 585–597 (1995).

    Article  CAS  PubMed  Google Scholar 

  10. Stegeman, C.A. et al. Ann. Intern. Med. 120, 12–17 (1994).

    Article  CAS  PubMed  Google Scholar 

  11. Stegeman, C.A. et al. N. Engl. J. Med. 335, 16–20 (1996).

    Article  CAS  PubMed  Google Scholar 

  12. Popa, E.R. & Cohen Tervaert, J.W. Intern. Med. 42, 771–780 (2003).

    Article  CAS  PubMed  Google Scholar 

  13. Pendergraft, W.F., III et al. Nat. Med. 10, 72–79 (2004).

    Article  CAS  PubMed  Google Scholar 

  14. Popa, E.R. et al. Rheumatology (Oxford) 46, 1029–1033 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kallenberg, C., Stegeman, C. & Heeringa, P. Autoantibodies vex the vasculature. Nat Med 14, 1018–1019 (2008). https://doi.org/10.1038/nm1008-1018

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm1008-1018

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing