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Targeted cancer treatment: resisting arrest

Many individuals with chronic myeloid leukemia have benefited from the drug imatinib (Gleevec)—but if they are taken off the drug, relapse occurs. Two mathematical models to explain this phenomenon, one described in this issue, have come to different conclusions (1181–1184).

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Figure 1: Dynamics of CML treatment with imatinib.

Kim Caesar


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Wodarz, D. Targeted cancer treatment: resisting arrest. Nat Med 12, 1125–1126 (2006).

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