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Fast track to the porphyrias

Nature Medicine volume 11, pages 1049–1050 (2005)Cite this article

In susceptible individuals, fasting can trigger an attack of acute porphyria—a syndrome caused by the neurotoxic effects of precursors to porphyrins. The mechanistic basis for this trigger is now uncovered.

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Figure 1: Regulation of heme biosynthesis in the liver.

Katie Ris

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Authors and Affiliations

  1. Division of Hematology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, 84132, Utah, USA

    John D Phillips & James P Kushner

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  1. John D Phillips
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  2. James P Kushner
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Phillips, J., Kushner, J. Fast track to the porphyrias. Nat Med 11, 1049–1050 (2005). https://doi.org/10.1038/nm1005-1049

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