The hormone adiponectin is secreted from fat cells and increases sensitivity to insulin in muscle and liver; adiponectin increases resistance to metabolic disorders and, it now appears, may also protect heart tissue when blood flow is restricted (pages 1096–1103).
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Rent or buy this article
Get just this article for as long as you need it
Prices may be subject to local taxes which are calculated during checkout
Shibata, R. et al. Nat. Med. 11, 1096–1103 (2005).
Kadowaki, T. & Yamauchi, T. Endocr. Rev. 26, 439–451 (2005).
Yamauchi, T. et al. Nature, 423, 762–769 (2003).
Yamauchi, T. et al. Nat. Med. 8, 1288–1295 (2002).
Berg, A.H. & Scherer, P.E. Circ. Res. 96, 939–949 (2005)
Pischon, T. et al. JAMA. 291, 1730–1737 (2004).
Russell III, R.R. et al. J. Clin. Invest. 114, 495–503 (2004).
Shibata, R. et al. Nat. Med. 10, 1384–1389 (2004).
Couzin, J. Science 306, 384–385 (2004).
Xiao, C.Y. et al. Circulation 109, 2462–2468 (2004).
Xiao, C.Y. et al. Circulation 104, 2210–2215 (2001).
Bolli, R. et al. Cardiovasc. Res. 55, 506–519 (2002).
Rights and permissions
About this article
Cite this article
Yuhki, Ki., Kawabe, Ji. & Ushikubi, F. Fat, keeping the heart healthy?. Nat Med 11, 1048–1049 (2005). https://doi.org/10.1038/nm1005-1048