Antibodies that stimulate T-cell costimulatory receptors block progression of established rheumatoid arthritis in a mouse model. No existing therapy arrests disease to such an extent (pages 1088–1094).
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Mittler, R. Suppressing the self in rheumatoid arthritis. Nat Med 10, 1047–1049 (2004). https://doi.org/10.1038/nm1004-1047
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DOI: https://doi.org/10.1038/nm1004-1047
