Bone marrow spawns brain killers

The reduction in blood flow to the brain that causes a stroke triggers a deadly cascade of events that can lead to brain death. Studies in mice show that activation of an adenosine receptor on neutrophils invading the brain from the blood contribute to the damage (pages 1081–1087).

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Figure 1: Adenosine aggravates neutrophils.

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Iadecola, C. Bone marrow spawns brain killers. Nat Med 10, 1044–1045 (2004). https://doi.org/10.1038/nm1004-1044

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