A safer stem cell: on guard against cancer

Before stem cell therapies become mainstream, several hurdles must be overcome. One challenge is developing air-tight approaches to assure that stem cell transplantation does not give rise to tumors. Another is finding safe ways to induce pluripotency in adult stem cells, which can then be used for transplantation. In Bedside to Bench, Evan Snyder and Rahul Jandial discuss the risks of tumorigenesis in stem cell therapies, and, in Bench to Bedside, Laura Clarke and Derek van der Kooy examine new ways to induce pluripotency.

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Figure 1: Human NSCs, maintained in culture and starting to differentiate into neurons.


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Correspondence to Evan Y Snyder.

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Jandial, R., Snyder, E. A safer stem cell: on guard against cancer. Nat Med 15, 999–1001 (2009). https://doi.org/10.1038/nm0909-999

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