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HDAC7 supports vascular integrity

A histone deacetylase regulates genes required for healthy blood vessels.

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Figure 1: HDAC7 mutant embryos show normal early development and patterning of the vascular endothelium, shown here in red staining for the marker Tie2.

Reprinted with permission of Cell Press

Figure 2: Regulation of vascular integrity by HDAC7.

Ann Thomson

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Miano, J., Berk, B. HDAC7 supports vascular integrity. Nat Med 12, 997–998 (2006). https://doi.org/10.1038/nm0906-997

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