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Keeping telomerase in its place

A new study shows that TERT, a component of telomerase, shuttles between nuclear compartments during the cell cycle. TERT localization is disrupted in cancer and following ionizing radiation, perhaps affecting genome stability.

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Figure 1: The telomerase shuttle.

Wong and Collins

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Maser, R., DePinho, R. Keeping telomerase in its place. Nat Med 8, 934–936 (2002). https://doi.org/10.1038/nm0902-934

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