Vaccines can prevent infections by several pathogens. Success, however, has been limited for other chronic diseases, reflecting a constraint for effectively manipulating the human immune system. The results from four studies describe a novel dendritic cell (DC) subset in humans that may be crucial for the design of vaccines against cancer and other chronic diseases.
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Gallois, A., Bhardwaj, N. A needle in the 'cancer vaccine' haystack. Nat Med 16, 854–856 (2010). https://doi.org/10.1038/nm0810-854
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DOI: https://doi.org/10.1038/nm0810-854