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Blocking and tackling HIV

Two studies suggest that low levels of antibodies, when present continuously, effectively limit or prevent HIV infection (pages 951–954 and 901–906). The findings provide hope for the development of a vaccine.

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Figure 1: Schematic representation of how the balance between the size of the virus inoculum and the amount of neutralizing antibody affects the outcome of SIV and SHIV infection of macaques.

Katie Vicari

References

  1. Igarashi, T. et al. Nat. Med. 5, 211–216 (1999).

    Article  CAS  Google Scholar 

  2. Haigwood, N.L. et al. J. Virol. 78, 5983–5995 (2004).

    Article  CAS  Google Scholar 

  3. Nishimura, Y. et al. J. Virol. 76, 2123–2130 (2002).

    Article  CAS  Google Scholar 

  4. Hessell, A.J. et al. Nat. Med. 15, 951–954 (2009).

    Article  CAS  Google Scholar 

  5. Johnson, P.R. et al. Nat. Med. 15, 901–906 (2009).

    Article  CAS  Google Scholar 

  6. Hessell, A.J. et al. PLoS Pathog. 5, e1000433 (2009).

    Article  Google Scholar 

  7. Doria-Rose, N.A. et al. J. Virol. 83, 188–199 (2009).

    Article  CAS  Google Scholar 

  8. Mahalanabis, M. et al. J. Virol. 83, 662–672 (2009).

    Article  CAS  Google Scholar 

  9. Sather, D.N. et al. J. Virol. 83, 757–769 (2009).

    Article  CAS  Google Scholar 

  10. Wrammert, J. et al. Nature 453, 667–671 (2008).

    Article  CAS  Google Scholar 

  11. Scheid, J.F. et al. Nature 458, 636–640 (2009).

    Article  CAS  Google Scholar 

  12. Li, Y. et al. J. Virol. 83, 1045–1059 (2009).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Nancy L. Haigwood.

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Haigwood, N., Hirsch, V. Blocking and tackling HIV. Nat Med 15, 841–842 (2009). https://doi.org/10.1038/nm0809-841

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