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Putting pressure on pre-eclampsia

Women with pre-eclampsia, a potentially deadly complication of pregnancy, produce agonistic autoantibodies against angiotensin receptor-1, a transmembrane protein that regulates blood pressure. Findings in mice suggest how these antibodies might help trigger the condition (pages 855–862).

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Figure 1: Angiotensin receptor autoantibodies (AT1-AAs) in pre-eclampsia.

Katie Ris-Vicari

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Parikh, S., Karumanchi, S. Putting pressure on pre-eclampsia. Nat Med 14, 810–812 (2008). https://doi.org/10.1038/nm0808-810

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