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ALS: life and death in a bad neighborhood

The role of inflammatory mechanisms in amyotrophic lateral sclerosis is a hotly debated topic. Findings in a mouse model now add weight to arguments that targeting of inflammatory cells might be a fruitful therapeutic approach.

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Figure 1: Microglia respond to several types of immunological alarm signals.

Kim Caesar

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Monk, P., Shaw, P. ALS: life and death in a bad neighborhood. Nat Med 12, 885–887 (2006). https://doi.org/10.1038/nm0806-885

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