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Gene delivery goes global

Nature Medicine volume 10, pages 782783 (2004) | Download Citation

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For gene therapy of muscular dystrophies, all of the skeletal muscles in the body must be transduced—a tough challenge. An approach that permeabilizes blood vessels using VEGF, helping low doses of a parvovirus-based gene therapy vector sneak across the vessel wall, now solves this problem in mice (pages 828–834).

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Affiliations

  1. Clare E. Thomas is an Associate Editor at Nature Medicine. c.thomas@natureny.com

    • Clare E Thomas

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DOI

https://doi.org/10.1038/nm0804-782

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