Can tumor progression be understood in terms of the redeployment of mechanisms used in embryonic development? The identification of Twist, a bHLH transcription factor, as a protein linked to metastases in breast cancers would suggest so.
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References
Yang, J. et al. Cell 117, 927–939 (2004).
Thisse, B. el Messal, M. & Perrin-Schmitt, F. Nucleic Acids Res. 15, 3439–3453 (1987).
Leptin, M. & Grunewald, B. Development 110, 73–84 (1990).
el Ghouzzi, V. et al. Nat. Genet. 15, 42–46 (1997).
Bolos, V. et al. J. Cell Sci. 116, 499–511 (2003).
Comijn, J. et al. Mol. Cell 7, 1267–1278 (2001).
Thiery, J.P. Nat. Rev. Cancer 2, 442–454 (2002).
Berx, G. & Van Roy, F. Breast Cancer Res. 3, 289–293 (2001).
Fatteneh, T. & Peter, D. (eds.) Pathology and Genetics of Tumours of the Breast and Female Genital Organs, 432 (IARC Press, Lyon, 2003).
Ferlicot, S. et al. Eur. J. Cancer 40, 336–341 (2004).
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Thiery, J., Morgan, M. Breast cancer progression with a Twist. Nat Med 10, 777–778 (2004). https://doi.org/10.1038/nm0804-777
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DOI: https://doi.org/10.1038/nm0804-777
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