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RNAi quashes polyQ

Nature Medicine volume 10, pages 775776 (2004) | Download Citation

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RNA interference in the brain inhibits neurodegeneration in a polyglutamine disease, SCA1. Is this now the way forward for the clinical treatment of certain genetic disorders (pages 816–820)?

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Affiliations

  1. Natasha J. Caplen is at the Gene Silencing Section, Office of Science and Technology Partnerships, Office of the Director, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA. ncaplen@mail.nih.gov

    • Natasha J Caplen

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DOI

https://doi.org/10.1038/nm0804-775

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