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RNAi quashes polyQ

RNA interference in the brain inhibits neurodegeneration in a polyglutamine disease, SCA1. Is this now the way forward for the clinical treatment of certain genetic disorders (pages 816–820)?

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Figure 1: Nixing neurodegeneration.

Renee Lucas

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Caplen, N. RNAi quashes polyQ. Nat Med 10, 775–776 (2004). https://doi.org/10.1038/nm0804-775

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  • DOI: https://doi.org/10.1038/nm0804-775

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