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The psychobiological regulation of social cooperation

Nature Medicine volume 1, pages 623–624 (1995)Cite this article

Dynamic interactions between multiple factors underlie alcoholism, including recently described neuroregulatory influences (pages 654–657).

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References

  1. Tiihonen, J. et al. Altered striatal dopamine re-uptake site densities in habitually violent and nonviolent alcoholics. Nature Med. 1, 654–657 (1995).

    Article  CAS  Google Scholar 

  2. Cloninger, C.R. Neurogenetic adaptive mechanisms in alcoholism. Science 236, 410–416 (1987).

    Article  CAS  Google Scholar 

  3. Cloninger, C.R., Przybeck, T.R., Svrakic, D.M. & Wetzel, R. The Temperament and Character Inventory: A Guide to its Development and Use. (Washington University Center for Psychobiology of Personality, St. Louis, Missouri, 1994).

    Google Scholar 

  4. Menza, M.A., Globe, L.I., Cody, R.A. & Forman, N.E. Dopamine-related personality traits in Parkinson's disease. Neurology 43, 505–508 (1993).

    Article  CAS  Google Scholar 

  5. Menza, M.A., Forman, N.E., Sage, J.I. & Golbe, L.I. Parkinson's disease and smoking: The relationship to personality. Neuropsychiat. behav. Neurol. 6, 214–218 (1993)

    Google Scholar 

  6. Menza, M.A., Mark, M.H., Burn, D.J. & Brooks, D.J. Psychiatric correlates of 18F-dopa striatal uptake: Results of positron emission tomography in Parkinson's disease. J. Neuropsychiat clin, Neurosci. (in the press).

  7. Simonsson, P., Berglund, M., Oreland, L., Moberg, A.-L. & Ailing, C. Serotonin-stimulated phosphoinositide hydrolysis in platelets from post-withdrawal alcoholics. Alcohol & Alcoholism 27, 607–612.

  8. Svrakic, D.M., Whitehead, C., Przybeck, T.R. & Cloninger, C.R. Differential diagnosis of personality disorders by the seven factor model of temperament and character. Archs gen. Psychiat. 50, 991–999 (1993).

    Article  CAS  Google Scholar 

  9. Cloninger, C.R., Sigvardsson, S. & Bohman, M. Childhood personality predicts alcohol abuse in young adults. Alcoholism 13, 494–505.

    Article  CAS  Google Scholar 

  10. Cloninger, C.R., Svrakic, D.M. & Przybeck, T.R. A psychobiological model of temperament and character. Archs gen. Psychiat. 50, 975–990 (1993).

    Article  CAS  Google Scholar 

  11. Virkkunen, M. et al. Personality profiles and state aggressiveness in Finnish alcoholic, violent offenders, fire setters, and healthy volunteers. Archs gen. Psychiat. 51, 28–33 (1994).

    Article  CAS  Google Scholar 

  12. Benkelfat, C. et al. Ethanollike properties of the serotonergic partial aganist m-chlorophenyl-piperazine in chronic alcoholic patients. Archs gen. Psychiat. 48, 383 (1991).

    Article  CAS  Google Scholar 

  13. Kruesi, M.J. et al. Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents. Archs gen. Psychiat. 47, 419–426 (1990).

    Article  CAS  Google Scholar 

  14. Svrakic, N., Svrakic, D.M. & Cloninger, C.R. A general quantitative model of personality development: Fundamentals of a self-organizing psychobiological complex. Dev. Psychopath. (in the press).

  15. Higley, J.D. et al. Paternal and maternal genetic and environmental contributions to CSF monoamine metabolite concentrations in rhesus monkeys (Macaca mulatta). Archs gen. Psychiat 50, 615–623 (1993).

    Article  CAS  Google Scholar 

  16. Iimson, R. et al. Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls. Archs gen. Psychiat. 48, 437–441 (1991).

    Article  Google Scholar 

  17. Stallings, M.C., Hewitt, J.K., Cloninger, C.R., Heath, A.C. & Eaves, L.J. Genetic and environmental structure of the Tridimensional Personality Questionnaire: Three or four factors? J. pers. soc. Psychol. (in the press).

  18. Jibson, M., Faull, K.F. & Csernansky, J.G. Intercorrelations among monoamine metabolite concentrations in human lumbar CSF are not due to a shared acid transport system. Biol. Psychiat. 28, 595–602 (1990).

    Article  CAS  Google Scholar 

  19. Agren, H., Mefford, I.N., Rudorfer, M.V., Linnoila, M. & Potter, W.Z. Interacting neurotrans-mitter systems. A non-experimental approach to the 5HIAA-HVA correlation in human CSF. J. Psychiat Res. 20, 175–193 (1986).

    Article  CAS  Google Scholar 

  20. Goldman, D. et al. D2 dopamine receptor genotype and cerebrospinal fluid homovanillic acid, 5-hydrox-yindoleacetic acid and 3-methoxy-4-hydroxphenyl-glycol in alcoholics in Finland and the United States. Acta psychiat Scand. 86, 351–357 (1992).

    Article  CAS  Google Scholar 

  21. Krystal, J.H., Webb, E., Cooney, N., Kranzler, H.R. & Charney, D.S. Specificity of ethanollike effects elicited by serotonergic and noradrenergic mechanisms. Archs gen. Psychiat 51, 898–911 (1994).

    Article  CAS  Google Scholar 

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  1. Departments of Psychiatry and Genetics Center for Psychobiology of Personality Washington University School of Medicine St. Louis, Missouri, 63110, USA

    C.Robert Cloninger

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  1. C.Robert Cloninger
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Cloninger, C. The psychobiological regulation of social cooperation. Nat Med 1, 623–624 (1995). https://doi.org/10.1038/nm0795-623

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