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The problem with upward mobility

In psoriasis, expression of the α1β1 integrin is necessary for T cells to enter the epidermis to cause inflammation and psoriatic lesions (pages 836–842).

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Figure 1: Antibodies to α1β1 integrin block emigration of T cells into the epidermis, aborting development of psoriasis lesions.

Katie Ris

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Gudjonsson, J., Elder, J. The problem with upward mobility. Nat Med 13, 786–787 (2007). https://doi.org/10.1038/nm0707-786

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