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Pulmonary barriers to pneumonia and sepsis

Nature Medicine volume 13, pages 780–781 (2007)Cite this article

In a new role for an ion transporter, Na+-K+-Cl− cotransporter-1 may regulate the lung endothelial and epithelial barriers and consequently modulate the host response to pneumonia and sepsis.

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Figure 1: Possible mechanisms that could explain how Na+-K+-Cl− transporter-1 (NKCC1) contributes to pulmonary edema and neutrophil transmigration into the air spaces.

Katie Ris

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Authors and Affiliations

  1. Michael A. Matthay and Xiao Su are in the Departments of Medicine and Anesthesia in the Cardiovascular Research Institute, University of California, 505 Parnassus Avenue M917, San Francisco, California 94143, USA. michael.matthay@ucsf.edu,

    Michael A Matthay & Xiao Su

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  1. Michael A Matthay
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  2. Xiao Su
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Matthay, M., Su, X. Pulmonary barriers to pneumonia and sepsis. Nat Med 13, 780–781 (2007). https://doi.org/10.1038/nm0707-780

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