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Aβ star: a light onto synaptic dysfunction?

Learning and memory is impaired in a mouse model of Alzheimer disease. An Aβ 12-mer called Aβ* may be responsible for these cognitive deficits.

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Figure 1: Aβ*56, most likely a tetramer of Aβ trimers, is the prime candidate suspected of causing early memory deficits in a mouse model of Alzheimer disease4.

Kim Caesar


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Kim, SH., Tang, YP. & Sisodia, S. Aβ star: a light onto synaptic dysfunction?. Nat Med 12, 760–761 (2006).

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