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Pinpointing plaques with PIB

The promise of disease-modifying treatments for Alzheimer disease calls for biomarkers that enable early diagnosis. A new discovery shows how to visualize amyloid pathology in living Alzheimer patients.

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Figure 1: PET images produced using Pittsburgh Compound-B (PIB) shown in sagittal (top) and transaxial (bottom) views.

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Blennow, K., Zetterberg, H. Pinpointing plaques with PIB. Nat Med 12, 753–754 (2006). https://doi.org/10.1038/nm0706-753

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