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Brain on steroids resists neurodegeneration

A single injection of the neurosteroid allopregnanolone can delay the onset of neurological symptoms, decrease neuronal cell death and double the lifespan of mice with Niemann–Pick type C disease (pages 704–711).

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Figure 1: NP-C and steroids.

Kimberly Caesar


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Burns, M., Duff, K. Brain on steroids resists neurodegeneration. Nat Med 10, 675–676 (2004).

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