A single injection of the neurosteroid allopregnanolone can delay the onset of neurological symptoms, decrease neuronal cell death and double the lifespan of mice with Niemann–Pick type C disease (pages 704–711).
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Burns, M., Duff, K. Brain on steroids resists neurodegeneration. Nat Med 10, 675–676 (2004). https://doi.org/10.1038/nm0704-675
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DOI: https://doi.org/10.1038/nm0704-675
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